Hanamichi Sakuragi, infamous for his temper, massive height, and fire-red hair, enrolls in Shohoku High, hoping to finally get a girlfriend and break his record of being rejected 50 consecutive times in middle school. His notoriety precedes him, however, leading to him being avoided by most students. Soon, after certain events, Hanamichi is left with two unwavering thoughts: "I hate basketball," and "I desperately need a girlfriend." One day, a girl named Haruko Akagi approaches him without any knowledge of his troublemaking ways and asks him if he likes basketball. Hanamichi immediately falls head over heels in love with her, blurting out a fervent affirmative. She then leads him to the gymnasium, where she asks him if he can do a slam dunk. In an attempt to impress Haruko, he makes the leap, but overshoots, instead slamming his head straight into the blackboard. When Haruko informs the basketball team's captain of Hanamichi's near-inhuman physical capabilities, he slowly finds himself drawn into the camaraderie and competition of the sport he had previously held resentment for. [Written by MAL Rewrite]

Sakamichi Onoda is a cheerful otaku looking to join his new school's anime club, eager to finally make some friends. Unfortunately, the club has been disbanded and he takes it upon himself to revive it by finding students who are willing to join. Without much luck, Onoda decides to make a round trip to Akihabara on his old, bulky city bicycle, a weekly 90-kilometer ride he has been completing since fourth grade. This is when he meets fellow first year student, Shunsuke Imaizumi, a determined cyclist who is using the school's steep incline for practice. Surprised by Onoda's ability to climb the hill with his specific type of bicycle, Imaizumi challenges him to a race, with the proposition of joining the anime club should Onoda win. And thus begins the young boy's first foray into the world of high school bicycle racing! [Written by MAL Rewrite]

Yabuki Joe is left downhearted and hopeless after a certain tragic event. In attempt to put the past behind him, Joe leaves the gym behind and begins wandering. On his travels he comes across the likes of Wolf Kanagushi and Goromaki Gondo, men who unintentionally fan the dying embers inside him, leading him to putting his wanderings to an end. His return home puts Joe back on the path to boxing, but unknown to himself and his trainer, he now suffers deep-set issues holding him back from fighting. In attempt to quell those issues, Carlos Rivera, a world renowned boxer is invited from Venezuela to help Joe recover.

Toua Tokuchi is an athlete by profession, but a reckless gambler at heart. On the streets of Okinawa, he uses nothing but his wits and a "fastball" peaking at a mere 134 kmph to somehow achieve 499 wins in the game of "One Outs," a simplified version of baseball between the pitcher and one batter. Amazed by Toua's unique prowess on the mound, veteran slugger Hiromichi Kojima artfully scouts the pitcher for his long unsuccessful team, the Saikyou Saitama Lycaons. Kojima desperately hopes Toua will lead them to the championship; however, Tsuneo Saikawa, the mercenary owner of the Lycaons, sees the vastly talented pitcher as a threat to the income generated by the team. Rising to the challenge of swaying the owner, Toua suggests a one-of-a-kind "One Outs" contract: every out Toua pitches will earn him five million yen, but with every run he gives up, he will lose fifty million yen. Adapted from the manga by Shinobu Kaitani of Liar Game fame, One Outs documents the intense psychological battles between Toua and those around him. With millions of yen at stake, can a pitcher who has done nothing but gamble in a head-to-head imitation of baseball finally lead a real baseball team to victory? [Written by MAL Rewrite]