Shortly after waking up in an unknown street with no clothes or memories, Retro and Pandy team up and begin a life of thrill chasing and violence. Retro's wild antics and Pandy's carefree personality make them the perfect partners in crime to cause mayhem wherever they strike. When an accidental mistake lands them behind bars, Retro and Pandy are sent to Dead Leaves—a high-security prison on the Moon. Once there, they soon discover that the other inmates are clones, all products of genetic mutation experiments. With nothing better to do, they escape from their cell and lead a prison break with the other captives. Armed with a crew of mutants and a hunger for havoc, the chaotic duo begins their wacky escape. Pandy and Retro awaken naked on Earth with no recollection of their past. They embark on a devastating crime spree in search of food, clothing and transportation, but are captured by authorities and sent to the infamous lunar penitentiary named Dead Leaves. While incarcerated, they quickly discover that Dead Leaves is also a top-secret cloning facility, occupied by villainous guards and deformed genetic experiments. Ultra-manic chaos and hyper-violent bedlam ensue as they organize a prison break with the aid of their fellow mutant inmates.