In the story of the anime, one day a black meteorite fell on the world, and the world completely changed. The meteorite produced grotesque monsters called D2, which started running rampant. D2 very quickly banned all music, which was the one thing able to overcome them. But there were some people who resisted the D2. They are young women who hold the power of music, the Musicart. These young women hold scores that are able to defeat the monsters. And there are also people who lead these women, the Conductor.